The overall in-hospital mortality was 17.1%. At last, nomogram and Kaplan-Meier curves were drawn to validate the model.Ī total of 181 patients who met Sepsis 3.0 criteria received CRRT were included in the study, in which, there were 31 deaths and 150 survivals during hospitalization, respectively. Adaptive LASSO for the Cox regression model was constructed by STATA software. According to the survival status, patients were split into death or survival group. Among them, patients who received CRRT during ICU hospitalization were included in this study. Patients who met the Sepsis-3.0 definition were identified using the MIMIC-III v1.4. The aim of this study was to develop an adaptive least absolute shrinkage and selection operator ( LASSO) for the Cox regression model to predict the hospital mortality in patients with Sepsis-3.0 undergoing CRRT using Medical Information Martin Intensive Care (MIMIC)-III v1.4.
Continuous renal replacement therapy (CRRT) is recommended as an adjuvant therapy for hemodynamics management in patients with sepsis. Sepsis remains the leading cause of mortality in-hospital in the intensive care unit (ICU).